Description

Peptide A5K (INF7-A5K-TAT acetate) acetate is a INF7-TAT derivative and is used for CRISPR RNP delivery into T cells. Peptide A5K acetate effectively promotes the delivery of Cas9 RNP to natural killer (NK) cells[1].—Cancer-programmed cell death–C182H275N55O48S.xC2H4O2—-[1]Dana V Foss, et al. Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes. Nat Biomed Eng. 2023 May;7(5):647-660.—-4033.54 (free acid)—-O=C(CN)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CC1=CC=C(O)C=C1)=O)=O)CC2=CC=C(O)C=C2)=O)CC3=CNC4=CC=CC=C34)=O)=O)CC(O)=O)=O)[C@H](CC)C)=O)CCSC)=O)=O)CCC(O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)CC(N)=O)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CC7=CC=CC=C7)=O)=O)CCC(O)=O)=O)[C@H](CC)C)=O)CCCCN)=O)CCC(O)=O)=O)CC8=CC=CC=C8)=O)CC(C)C.CC(O)=O.[x]–Cancer–10 mM in DMSO–Others—-Others–Peptides