Description

Pep2-8 is a PCSK9 inhibitor with a binding KD of 0.7 μM and an IC50 of 1.4 μM[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)–Metabolism-protein/nucleotide metabolism–C83H110N16O24—-[1]Yingnan Zhang, et al. Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor. J Biol Chem. 2014 Jan 10;289(2):942-55.–1541011-97-5–1715.85–99.74–O=C(N[C@H](C(N)=O)C(C)C)[C@@H](NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](CO)NC([C@@]([C@H](O)C)([H])NC([C@@H](NC([C@H](C(C)C)NC([C@H]([C@H](O)C)NC(C)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)=O)CC5=CNC6=CC=CC=C56–Cancer–DMSO : 100 mg/mL (ultrasonic)–Ser/Thr Protease—-Metabolic Enzyme/Protease–Peptides