Description

PEG4-aminooxy-MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the potent antitubulin agent MMAF, linked via the noncleavable PEG4[1].–20°C (Powder, protect from light)-Applications-Cancer-programmed cell death-Formula-C47H82N6O12-Citation–References-[1]Samantha Congreve, et al. Antibody drug conjugates (ADC). Teknisk- naturvetenskaplig fakultet-CASNumber-1415246-35-3-MolecularWeight-923.19-Compound Purity-99.83-SMILES-OC([C@H](CC1=CC=CC=C1)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCOCCOCCOCCON)=O)=O)=O)OC)=O)=O-Research_Area-Cancer; Inflammation/Immunology-Solubility-DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL-Target-Drug-Linker Conjugates for ADC;Microtubule/Tubulin-Isoform-Auristatin-Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton-MCE Product type-ADC Related