Description

PB089 is a Drug-liker containing a PEG unit and a cleavable linker attached to Exatecan[1].–20°C (Powder, sealed storage, away from moisture and light)-Applications-Cancer-programmed cell death-Formula-C90H133FN12O32-Citation–References-[1]Xiao, S, et, al. Linkers, drug linkers and conjugates thereof and methods of using the same. WO2023280227A2.|[2]Xiao, S, et, al. Linkers, drug linkers and conjugates thereof and methods of using the same. WO2023280227A2.-CASNumber-2892336-54-6-MolecularWeight-1914.08-Compound Purity-99.98-SMILES-O=C(OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN(C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)NC(CCCCCN(C2=O)C(C=C2)=O)=O)=O)=O)=O)N[C@@H]3C(C4=C5CC3)=C(CN6C7=CC([C@@]8(O)CC)=C(COC8=O)C6=O)C7=NC4=CC(F)=C5C-Research_Area-Cancer-Solubility-DMSO : 100 mg/mL (ultrasonic)-Target-Drug-Linker Conjugates for ADC-Isoform–Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related