P8RI-5 mg
Description
P8RI (D-P8RI) is a biomimetic peptide of CD31 and a CD31 agonist. P8RI binds to the juxtamembrane amino acid sequence of the ectodomain of CD31, shows an immunosuppressive effect through restoration of the CD31 inhibitory pathway[1][2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)–COVID-19-immunoregulation–C51H77N13O9—-[1]Diaz-Rodriguez S, et al. Coronary stent CD31-mimetic coating favours endothelialization and reduces local inflammation and neointimal development in vivo. Eur Heart J. 2021;42(18):1760-1769. |[2]Sannier A, et al. A CD31-Derived Peptide Prevents the Development of Antibody-Mediated Lesions in a Rat Model of Aortic Allograft. Transplant Proc. 2021;53(2):746-749. |[3]Andreata F, et al. Macrophage CD31 Signaling in Dissecting Aortic Aneurysm. J Am Coll Cardiol. 2018;72(1):45-57.–2147724-76-1–1016.24–99.70–O=C(N1[C@H](CCC1)C(N[C@H](C)C(N[C@H](CC(C)C)C(N[C@@H](C(N[C@H](C(C)C)C(N[C@@H](C(O)=O)CCCNC(N)=N)=O)=O)CC2=CC=CC=C2)=O)=O)=O)[C@H](NC([C@H](N)CCCCN)=O)CC3=CNC4=CC=CC=C34–Inflammation/Immunology–H2O : 100 mg/mL (ultrasonic)–Others—-Others–Peptides