OXA(17-33) (TFA)-Get quote

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OXA(17-33) TFA is a potent and selective orexin-1 receptor (OX1) agonist. OXA(17-33) TFA shows a ∼23-fold selectivity for the OX1 (EC50=8.29 nM) over OX2 (187 nM)[1].—Neuroscience-Neuromodulation–C81H126F3N23O24—-[1]German NA, et al. Truncated Orexin Peptides: Structure-Activity Relationship Studies. ACS Med Chem Lett. 2013;4(12):1224-1227.—-1863.00—-OC(C(F)(F)F)=O.OC(C=C1)=CC=C1C[C@H](N)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CN=CN2)C(NCC(N[C@@H](C)C(NCC(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](C)C(N[C@@H](C)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@H](C(N)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)=O)=O)=O)=O)=O–Neurological Disease–10 mM in DMSO–Orexin Receptor (OX Receptor)–OX1 Receptor;OX2 Receptor–GPCR/G Protein;Neuronal Signaling–Peptides