Description

Osteostatin (human), a fragment of parathyroid hormone-related protein (PTHrP) 107-139, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis[1].—–C142H228N42O58—-[1]Lidia Ibáñez, et al. Osteostatin Inhibits M-CSF+RANKL-Induced Human Osteoclast Differentiation by Modulating NFATc1. Int J Mol Sci. 2022 Aug 1;23(15):8551.|[2]C Heras, et al. Osteostatin potentiates the bioactivity of mesoporous glass scaffolds containing Zn2+ ions in human mesenchymal stem cells. Acta Biomater. 2019 Apr 15;89:359-371.–137348-10-8–3451.58—-N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CO)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](CO)NC([C@H]([C@H](O)C)NC([C@H]([C@H](O)C)NC([C@H](CO)NC([C@H]([C@H](O)C)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CC1=CN=CN1)NC([C@H](CC(O)=O)NC(CNC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CO)NC(CNC([C@H]([C@H](O)C)NC([C@H](C(C)C)NC(CNC([C@H](CO)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](C)NC([C@H](CO)NC([C@@H](NC([C@@H](N)[C@H](O)C)=O)CCCNC(N)=N)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O–Metabolic Disease; Inflammation/Immunology–10 mM in DMSO–Thyroid Hormone Receptor—-Vitamin D Related/Nuclear Receptor–Peptides