Description

Oseltamivir-d5 is the deuterium labeled Oseltamivir[1]. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50 of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[2].–Applications-COVID-19-anti-virus-Formula-C16H23D5N2O4-Citation–References-[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]O Ferraris, et al. Sensitivity of Influenza Viruses to Zanamivir and Oseltamivir: A Study Performed on Viruses Circulating in France Prior to the Introduction of Neuraminidase Inhibitors in Clinical Practice. Antiviral Res. 2005 Oct;68(1):43-8.-CASNumber-1093851-63-8-MolecularWeight-317.44-Compound Purity–SMILES-CCC(CC)O[C@H]1[C@@H]([C@H](CC(C(OC(C([2H])([2H])[2H])([2H])[2H])=O)=C1)N)NC(C)=O-Research_Area-Infection-Solubility-10 mM in DMSO-Target-Influenza Virus-Isoform–Pathway-Anti-infection-MCE Product type-Isotope-Labeled Compounds