Description

Oseltamivir-d3-1 is the deuterium labeled Oseltamivir[1]. Oseltamivir is an influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Anti-influenza A and B agent[2].–Applications-COVID-19-anti-virus-Formula-C16H25D3N2O4-Citation–References-[1]O Ferraris, et al. Sensitivity of Influenza Viruses to Zanamivir and Oseltamivir: A Study Performed on Viruses Circulating in France Prior to the Introduction of Neuraminidase Inhibitors in Clinical Practice. Antiviral Res. 2005 Oct;68(1):43-8. |[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.-CASNumber–MolecularWeight-315.42-Compound Purity–SMILES-O=C(OCC([2H])([2H])[2H])C1=C[C@H]([C@@H]([C@H](C1)N)NC(C)=O)OC(CC)CC-Research_Area-Infection-Solubility-10 mM in DMSO-Target-Influenza Virus-Isoform–Pathway-Anti-infection-MCE Product type-Isotope-Labeled Compounds