Description

Orexin A (human, rat, mouse) (Hypocretin-1 (human, rat, mouse)), a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A (human, rat, mouse) is a specific, high-affinity agonist for G-protein-coupled receptor OX1R. Orexin A (human, rat, mouse) has a role in the regulation of feeding behavior. Orexin A (human, rat, mouse) is an effective anti-nociceptive and anti-hyperalgesic agent in mice and rats[1][2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–Neuroscience-Neuromodulation–C152H243N47O44S4—-[1]Bingham S, et al. Orexin-A, an hypothalamic peptide with analgesic properties. Pain. 2001 May;92(1-2):81-90.|[2]Sakurai T, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 1998 Feb 20;92(4):573-85.–205640-90-0–3561.10–99.67–O=C([C@H]1N(CCC1)C([C@@H]2CCC(N2)=O)=O)N[C@@H](CC(C)C)C(N3[C@@H](CCC3)C(N[C@@H](CC(O)=O)C(N[C@@H]4C(N[C@]5([H])C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@](C(N[C@@](C(N[C@H](C(N[C@@H](CSSC5)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@H](C(NCC(N[C@@H](C)C(NCC(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](C)C(N[C@@H](C)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@H](C(N)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)CC6=CN=CN6)=O)=O)=O)=O)=O)CC7=CN=CN7)=O)=O)=O)=O)CC8=CC=C(C=C8)O)=O)=O)=O)=O)CO)=O)([H])CSSC4)=O)([H])[C@H](O)C)=O)CCCCN)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O–Neurological Disease–H2O : ≥ 50 mg/mL–Orexin Receptor (OX Receptor)–OX1 Receptor–GPCR/G Protein;Neuronal Signaling–Peptides