Description

OB3, a derivative of Leptin, show more effective than leptin in reducing obesity and diabetes in mouse models. OB3 can reduce Leptin-related inflammation and proliferation in hepatocellular carcinoma cells[1].—Metabolism-protein/nucleotide metabolism–C29H50N8O12S—-[1]Ho Y, et, al. Leptin-derived peptides block leptin-induced proliferation by reducing expression of pro-inflammatory genes in hepatocellular carcinoma cells. Food Chem Toxicol. 2019 Nov;133:110808. –259535-56-3–734.82—-C[C@@H](O)[C@@H](C(O)=O)NC([C@H](CCC(N)=O)NC([C@H]1N(CCC1)C([C@H](CC(C)C)NC([C@H](CO)NC([C@H](CS)NC([C@@H](N)CO)=O)=O)=O)=O)=O)=O–Cancer; Metabolic Disease; Inflammation/Immunology–H2O–Others—-Others–Peptides