Description

NPC-567 is a bradykinin B2 receptor antagonist. NPC-567 is effective in inhibiting the acute response to allergen in the airways[1][2].—COVID-19-immunoregulation–C60H87N19O13—-[1]Sylvin H, et al. The effect of a bradykinin B2 receptor antagonist, NPC-567, on allergen-induced airway responses in a porcine model. Inflamm Res. 2001 Sep;50(9):453-9.|[2]Cheronis JC, et al. A new class of bradykinin antagonists: synthesis and in vitro activity of bissuccinimidoalkane peptide dimers. J Med Chem. 1992 May 1;35(9):1563-72.–109333-26-8–1282.45—-O=C(N[C@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CC2=CC=CC=C2)=O)[C@H](CO)NC([C@@H](NC(CNC([C@H]3N(C([C@H]4N(C([C@@H](NC([C@H](N)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC4)=O)C[C@H](O)C3)=O)=O)CC5=CC=CC=C5)=O–Inflammation/Immunology–10 mM in DMSO–Bradykinin Receptor—-GPCR/G Protein–Peptides