Description

NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].-4°C (Powder, protect from light)-Applications-Cancer-programmed cell death-Formula-C19H39NO8-Citation–References-[1]Foley CA, et al. Assessing the Cell Permeability of Bivalent Chemical Degraders Using the Chloroalkane Penetration Assay. ACS Chem Biol. 2020 Jan 17;15(1):290-295.|[2]Kenneth John DIRICO, et al. Spliceostatin analogs. WO2014068443A1.-CASNumber-1286281-32-0-MolecularWeight-409.51-Compound Purity-97.0-SMILES-O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCN-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker;PROTAC Linkers-Isoform-Alkyl/ether Linkers;Non-cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related