Description

NFF-3 TFA, the peptide, is a selective MMP substrate. NFF-3 TFA selectively binds to MMP-3 and MMP-10 to be hydrolyzed. NFF-3 TFA is also cleaved by trypsin, hepatocyte growth factor activator, and factor Xa. Label NFF-3 TFA with a CyDye pair, Cy3/Cy5Q, can produce fluorescence in cell assays to detect cell activity[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)—-C80H111F3N22O22—-[1]Giricz O, et al. Comparison of metalloproteinase protein and activity profiling. Anal Biochem. 2011 Feb 1;409(1):37-45.—-1789.87–98.57–O=[N+]([O-])C(C=C(C=C1)[N+]([O-])=O)=C1NCCCC[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CCC)NC([C@H](CCC(O)=O)NC([C@H](C(C)C)NC([C@H]2N(CCC2)C([C@H](CCCCN)NC([C@H]3N(CCC3)C([C@H](CCCNC(N)=N)NC(CC(C4=CC=C(OC)C=C4O5)=CC5=O)=O)=O)=O)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O.OC(C(F)(F)F)=O–Others–DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : < 0.1 mg/mL (ultrasonic;adjust pH to 2 with HCl)–MMP–MMP-10;MMP-3–Metabolic Enzyme/Protease–Peptides