Description

:APC;host:Rabbit;target_protein:Nestin;modification:Unmodified;clonality:Polyclonal;isotype:IgG;concentration:1ug/ul;subcellular_locations:Cytoplasm;source:KLH conjugated synthetic peptide derived from rat Nestin;gene_id:25491;swiss_prot:P21263;applications_with_dilutions:FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200);cross_reactive_species:Human, Mouse, Rat;predicted_cross_reactive_species:;background:Required for brain and eye development (By similarity). Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.;purification:Purified by Protein A.;storage_buffer:Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.;storage_condition:Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.;:650nm/660nm;synonyms:ESTM 46; FLJ 21841; FLJ21841; Intermediate filament protein; Nbla00170; Nes; NEST_RAT; Nestin.