Description

N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability[1].-Solution, -20°C, 2 years-Applications-Cancer-programmed cell death-Formula-C10H14N2Na3O15P3-Citation–References-[1]Andries O, Mc Cafferty S, De Smedt SC, Weiss R, Sanders NN, Kitada T. N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice. J Control Release. 2015;217:337-344. -CASNumber–MolecularWeight-564.11-Compound Purity-99.0-SMILES-O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O[C@@H]1COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O-Research_Area-Others-Solubility-H2O : 10 mg/mL (ultrasonic)-Target-DNA/RNA Synthesis;Nucleoside Antimetabolite/Analog-Isoform–Pathway-Cell Cycle/DNA Damage-MCE Product type-Biochemical Assay Reagents