Description

N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) )[1].–20°C (Powder, stored under nitrogen)-Applications-Cancer-programmed cell death-Formula-C9H13NO3-Citation–References-[1] Finniss, M. C., et al. A versatile acid-labile linker for antibody–drug conjugates. Med. Chem. Commun., 2014, 5(9), 1355-1358.-CASNumber-180608-78-0-MolecularWeight-183.20-Compound Purity-99.89-SMILES-OCCCCCN1C(C=CC1=O)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform-Non-cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related