Description

Monomethyl auristatin E (MMAE) (GMP) is Monomethyl auristatin E (HY-15162) produced by using GMP guidelines. Monomethyl auristatin E is a tubulin polymerization inhibitor[1].–Applications-Cancer-programmed cell death-Formula-C39H67N5O7-Citation–References-[1]Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research (2010), 16(3), 888-897.-CASNumber-474645-27-7-MolecularWeight-717.98-Compound Purity–SMILES-CC(C)[C@H](NC)C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@@H](CC(N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)=O)OC)C)=O)C(C)C)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Cytotoxin;Apoptosis;Microtubule/Tubulin-Isoform–Pathway-Antibody-drug Conjugate/ADC Related;Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton-MCE Product type-GMP Small Molecules