Description

MMAD is a potent tubulin inhibitor, is a toxin payload in antibody agent conjugates (ADCs).-4°C (Powder, stored under nitrogen)-Applications-Cancer-programmed cell death-Formula-C41H66N6O6S-Citation–References-[1]Chudasama V, et al. Recent advances in the construction of antibody-drug conjugates. Nat Chem. 2016 Feb;8(2):114-9.-CASNumber-203849-91-6-MolecularWeight-771.06-Compound Purity-99.94-SMILES-O=C([C@H](C)[C@H]([C@]1([H])CCCN1C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C([C@@H](NC([C@@H](N(C)[H])C(C)C)=O)C(C)C)=O)C)=O)OC)N[C@@H](CC2=CC=CC=C2)C3=NC=CS3-Research_Area-Cancer-Solubility-DMSO : 24.5 mg/mL (ultrasonic;warming)-Target-ADC Cytotoxin;Microtubule/Tubulin-Isoform-Auristatin-Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton-MCE Product type-ADC Related