Description

Mitogen-activated protein kinase 1 (MAPK1) can activate the downstream p38/NF-κB pathway. Mitogen-activated protein kinase 1 can regulate cellular processes in various sepsis-associated diseases. MAPK-catalyzed phosphorylation of substrate proteins functions as a switch to turn on or off the activity of the substrate protein[1].–Applications-COVID-19-immunoregulation-Formula-N/A-Citation–References-[1]Haixia Wang, et al. LncRNA KCNQ1OT1 (potassium voltage-gated channel subfamily Q member 1 opposite strand/antisense transcript 1) aggravates acute kidney injury by activating p38/NF-κB pathway via miR-212-3p/MAPK1 (mitogen-activated protein kinase 1) axis in sepsis. Bioengineered. 2021 Dec;12(2):11353-11368.|[2]Gary L Johnson, et al. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science. 2002 Dec 6;298(5600):1911-2.-CASNumber-137632-08-7-MolecularWeight-N/A-Compound Purity–SMILES-[Mitogen-activated protein kinase 1]-Research_Area-Inflammation/Immunology-Solubility-10 mM in DMSO-Target-NF-κB;p38 MAPK-Isoform–Pathway-MAPK/ERK Pathway;NF-κB-MCE Product type-Enzyme