Description

Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension[1][2].—Neuroscience-Neuromodulation–C8H16N2O4S—-[1]Diana Højmark Omkvist, et al. Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs. Eur J Pharm Biopharm. 2011 Feb;77(2):327-31. |[2]Pan Wuguang, et al. Application of sulfur dipeptide for preparing antihypertensive drug or health care product. Patent WO2019006954. –14517-43-2–236.29—-O=C([C@@H](N)CCSC)N[C@H](C(O)=O)CO–Cardiovascular Disease–10 mM in DMSO–Angiotensin-converting Enzyme (ACE)—-Metabolic Enzyme/Protease–Peptides