Description

[MePhe7]-Neurokinin B is an neurokinin NK-3 receptor (NK3R) agonist with an IC50 value of 3 nM. [MePhe7]-Neurokinin B is a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion via activation of the neurokinin-3 receptor (NK3R)[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–Metabolism-protein/nucleotide metabolism–C60H81N13O14S2—-[1]Misu R, et, al. Structure-activity relationship study of tachykinin peptides for the development of novel neurokinin-3 receptor selective agonists. Bioorg Med Chem. 2013 Apr 15;21(8):2413-2417.–110880-53-0–1272.49–98.87–CC(C[C@H](NC(CNC([C@@H](N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N)CC(O)=O)=O)CCSC)=O)CC1=CN=CN1)=O)CC(O)=O)=O)CC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O)C)CC4=CC=CC=C4)=O)=O)C(N[C@H](C(N)=O)CCSC)=O)C–Endocrinology; Neurological Disease–DMSO : 20 mg/mL (ultrasonic)–Neurokinin Receptor–NK3–GPCR/G Protein;Neuronal Signaling–Peptides