Description

MeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor. MeOSuc-AAPV-CMK also inhibits cathepsin G and proteinase 3.MeOSuc-AAPV-CMK blocks the cleavage of adiponectin by leukocyte elastase[1].—–C22H35ClN4O7—-[1]Waki H, et al. Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1. Endocrinology. 2005 Feb;146(2):790-6.|[2]Middelhoven PJ, Vet al. Different proteolytic mechanisms involved in Fc gamma RIIIb shedding from human neutrophils. Clin Exp Immunol. 2001 Jul;125(1):169-75.–65144-34-5–502.99—-O=C(N[C@@H](C(C)C)C(CCl)=O)[C@H]1N(C([C@H](C)NC([C@H](C)NC(CCC(OC)=O)=O)=O)=O)CCC1–Others–10 mM in DMSO–Cathepsin;Elastase—-Metabolic Enzyme/Protease–Peptides