Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc-50 mg
Description
Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].–20°C, 3 years (Powder)-Applications-Cancer-programmed cell death-Formula-C38H40N2O14-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.-CASNumber-894096-02-7-MolecularWeight-748.73-Compound Purity-98.84-SMILES-O=C(OC)[C@@H](O1)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC2=CC=C(CO)C=C2NC(CCNC(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O)=O-Research_Area-Cancer-Solubility-DMSO : 125 mg/mL (ultrasonic)-Target-ADC Linker-Isoform-Cleavable Linker;Glycosidase Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related