Description

MC-VC-PAB-Cyclohexanediamine-Thailanstatin A is a Spliceostatin (HY-16466) analog, and a drug-linker conjugates for ADC, consisting of ADC Cytotoxin Thailanstatin A (HY-129589) and cleavable ADC linker (MC-vc-PAB). MC-VC-PAB-Cyclohexanediamine-Thailanstatin A can be used for ADC synthesis[1].–80°C, protect from light, stored under nitrogen-Applications–Formula-C63H91N9O16-Citation–References-[1]Dirico KJ, et al. Preparation of spliceostatin analog antibody conjugates for cancer treatment. World Intellectual Property Organization, WO2014068443 A1. 2014-05-08.-CASNumber-1609108-96-4-MolecularWeight-1230.45-Compound Purity-92.11-SMILES-O[C@H]1[C@@]2(C[C@H](O[C@@H]1/C=C/C(C)=C/C[C@H]3[C@H](C[C@H]([C@H](O3)C)NC(/C=C[C@H](C)OC(C)=O)=O)C)CC(N[C@@H]4CC[C@H](CC4)NC(OCC5=CC=C(C=C5)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)=O)=O)CO2-Research_Area-Cancer-Solubility-DMSO : 85 mg/mL (ultrasonic)-Target-DNA/RNA Synthesis;Drug-Linker Conjugates for ADC-Isoform–Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage-MCE Product type-ADC Related