Description

MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. MC-Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker.-4°C (Powder, sealed storage, away from moisture)-Applications-Cancer-programmed cell death-Formula-C53H60FN9O12-Citation–References-[1]Anish Thomas, et al. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016 Jun;17(6):e254-e262.-CASNumber-2504068-28-2-MolecularWeight-1034.10-Compound Purity-99.55-SMILES-O=C(OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN(C2=O)C(C=C2)=O)=O)=O)=O)N[C@@H]3C(C4=C5CC3)=C(CN6C7=CC([C@@]8(O)CC)=C(COC8=O)C6=O)C7=NC4=CC(F)=C5C-Research_Area-Cancer-Solubility-DMSO : 50 mg/mL (ultrasonic)-Target-Drug-Linker Conjugates for ADC;Topoisomerase-Isoform-Camptothecins-Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage-MCE Product type-ADC Related