Description

MC-Val-Cit-PAB-clindamycin is a agent-linker conjugate for ADC with potent antitumor activity by using clindamycin (a protein synthesis inhibitor), linked via the ADC linker MC-Val-Cit-PAB.-4°C (Powder, sealed storage, away from moisture)-Applications-Cancer-programmed cell death-Formula-C46H72Cl2N8O11S-Citation–References-[1]Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.-CASNumber-1639793-13-7-MolecularWeight-1016.08-Compound Purity-99.99-SMILES-C[C@H](Cl)[C@@]([C@@]1([H])O[C@@H]([C@H](O)[C@@H](O)[C@H]1O)SC)([H])NC([C@H]2[N+](C)(C[C@H](CCC)C2)CC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN4C(C=CC4=O)=O)=O)=O)=O)C=C3)=O.[Cl-]-Research_Area-Cancer-Solubility-DMSO : 110 mg/mL (ultrasonic)-Target-Drug-Linker Conjugates for ADC-Isoform-Traditional Cytotoxic Agents-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related