Description

MC-EVCit-PAB-MMAE (Linker-Payload 11) is a drug-linker conjugates for ADC. MC-EVCit-PAB-MMAE contains the ADCs linker (MC-EVCit-PAB) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1].-4°C (Powder, protect from light, stored under nitrogen)-Applications-Cancer-programmed cell death-Formula-C73H112N12O18-Citation–References-[1]Matsuda, Yutaka, et al. Conjugate of antibody and functional substance or salt of said conjugate, and compound for use in production of said conjugate or salt of said compound. Patent. WO2022255425.-CASNumber-2873452-49-2-MolecularWeight-1445.74-Compound Purity-99.04-SMILES-O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC(CCCCCN4C(C=CC4=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O-Research_Area-Cancer-Solubility-DMSO : 85 mg/mL (ultrasonic;warming;heat to 60°C)-Target-Drug-Linker Conjugates for ADC;Microtubule/Tubulin-Isoform–Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton-MCE Product type-ADC Related