Description

Mal-VC-PAB-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB [1].-4°C (Powder, sealed storage, away from moisture and light)-Applications-Cancer-programmed cell death-Formula-C61H82ClN9O17-Citation–References-[1]Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1.-CASNumber-1464051-44-2-MolecularWeight-1248.81-Compound Purity-99.12-SMILES-C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)C=C5)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1-Research_Area-Cancer-Solubility-DMSO : 75 mg/mL (ultrasonic)-Target-Drug-Linker Conjugates for ADC-Isoform-Maytansinoids-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related