Description

Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule[1]. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs.–20°C, 3 years; 4°C, 2 years (Powder)-Applications-Cancer-programmed cell death-Formula-C11H15NO6-Citation–References-[1]Zhao, Yongxin, et al. Cytotoxin molecule, conjugate and preparation method and application thereof. Faming Zhuanli Shenqing (2019), CN 109912683 A 20190621.-CASNumber-1374666-32-6-MolecularWeight-257.24-Compound Purity-97.0-SMILES-O=C(O)CCOCCOCCN1C(C=CC1=O)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related