Description

Mal-C6-α-Amanitin is a agent-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.–20°C (Powder, protect from light)-Applications-Cancer-programmed cell death-Formula-C55H78N12O17S-Citation–References-[1]Brian Lannutti,et al. Ror1 antibody immunoconjugates. WO2018237335A1.-CASNumber-1578249-76-9-MolecularWeight-1211.34-Compound Purity-98.48-SMILES-O=S1C2=C(C[C@]3([H])NC([C@](NC([C@@]4([H])N(C[C@H](O)C4)C([C@@](CC(N)=O)([H])NC([C@](NC(CNC([C@@]([C@@H](C)CC)([H])NC(CNC3=O)=O)=O)=O)([H])C1)=O)=O)=O)([H])[C@@H](C)[C@@H](O)CO)=O)C5=CC=C(OCCCCCCNC(CCCCCN6C(C=CC6=O)=O)=O)C=C5N2-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-Drug-Linker Conjugates for ADC-Isoform-Daunorubicins/Doxorubicins-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related