[Lys5,MeLeu9,Nle10]-NKA(4-10) (TFA)-Get quote

Description

[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA is a highly selective and potent NK2 receptor agonist, with an IC50 of 6.1 nM[1].—Neuroscience-Neuromodulation–C39H65N9O9.xC2HF3O2—-[1]G Chassaing, et al. Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay). Neuropeptides. 1991 Jun;19(2):91-5.|[2]M A Matuszek, et al. An investigation of tachykinin NK2 receptor subtypes in the rat. Eur J Pharmacol. 1998 Jul 3;352(1):103-9.—-803.99 (free base)—-OC(C(F)(F)F)=O.OC(C[C@H](N)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](C(C)C)C(NCC(N(C)[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCCC)=O)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O–Neurological Disease–H2O–Neurokinin Receptor—-GPCR/G Protein;Neuronal Signaling–Peptides