Description

Leptin (116-130) is a bioactive leptin fragment. Leptin (116-130) promotes AMPA receptor trafficking to synapses and facilitate activity-dependent hippocampal synaptic plasticity. Leptin (116-130) prevents hippocampal synaptic disruption and neuronal cell death in models of amyloid toxicity. Leptin (116-130) has the potential for the research of Alzheimer’s disease (AD)[1].—Neuroscience-Neurodegeneration–C64H108N18O25S—-[1] Malekizadeh Y, et al. A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin. Cereb Cortex. 2017;27(10):4769-4782.–189224-35-9–1561.72—-O=C([C@H]1N(CCC1)C([C@H](CC(C)C)NC([C@H](CO)NC([C@H](CS)NC([C@@H](N)CO)=O)=O)=O)=O)N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O–Neurological Disease–10 mM in DMSO–iGluR–AMPA Receptor–Membrane Transporter/Ion Channel;Neuronal Signaling–Peptides