KRpep-2d-5 mg

Description
KRpep-2d is a potent K-Ras inhibitor and inhibits proliferation of K-Ras-driven cancer cells. KRpep-2d can be used for cancer research[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)–Cancer-Kinase/protease–C108H182N44O25S2—-[1]Niida A, et al. Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2757-2761.–2098181-84-9–2561.02–95.09–O=C1N2C(CCC2)(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC3=CC=C(O)C=C3)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CO)C(=O)N[C@@H](CC4=CC=C(O)C=C4)C(=O)N[C@@H](CC(O)=O)C(=O)N5[C@](C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CSSC[C@@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC(C)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)(CCC5)[H])[H])[H]–Cancer–H2O : 50 mg/mL (ultrasonic)–Ras–K-Ras–GPCR/G Protein;MAPK/ERK Pathway–Peptides