Description

JTP10-△-TATi TFA is a selective JNK2 peptide inhibitor, with an IC50 of 92 nM, exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)–Cancer-Kinase/protease–C120H213F3N48O28—-[1]Tamer S. Kao, et al. Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration. ACS Chem Biol. 2011 Jun 17;6(6):658-66.—-2833.28–98.49–OC(C(F)(F)F)=O.O=C(NC(NCCC[C@@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(NCC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CCCNC(N)=N)N)=O)=N)CCCCCNC([C@H](CC1=CC=CC=C1)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@H]([C@H](O)C)NC([C@H]2N(C([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@@H]3N(OC(C)=O)CCC3)=O)=O)=O)CCC2)=O)=O)=O)=O)=O)=O)=O–Cancer—-JNK–JNK1;JNK2;JNK3–MAPK/ERK Pathway–Peptides