Description

JTP10-△-R9 TFA is a selective JNK2 peptide inhibitor, with an IC50 of 89 nM, exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–Cancer-Kinase/protease–C119H214F3N53O26—-[1]Tamer S. Kao, et al. Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration. ACS Chem Biol. 2011 Jun 17;6(6):658-66.—-2860.31–99.80–O=C(CCCCCNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]1N(CCC1)C([C@@H](NC([C@@H](NC([C@H]2N(CCC2)C(C)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CC(C)C)=O)CC(N)=O)=O)CC(C)C)=O)CC3=CC=CC=C3)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N.OC(C(F)(F)F)=O–Cancer–H2O : 25 mg/mL (ultrasonic)–JNK–JNK1;JNK2;JNK3–MAPK/ERK Pathway–Peptides