Description

JIP-1(153-163) TFA (TI-JIP TFA) is a peptide inhibitor of c-JNK, based on residues 153-163 of JNK-interacting protein-1 (JIP-1) (Modifications: Phe-11 = C-terminal amide)[1].—Cancer-Kinase/protease–C61H104N20O14.xC2HF3O2—-[1]Renae K Barr, et al. Identification of the critical features of a small peptide inhibitor of JNK activity. J Biol Chem. 2002 Mar 29;277(13):10987-97.—-1341.60 (free base)—-OC(C(F)(F)F)=O.O=C([C@H]1N(CCC1)C([C@@H](N)CCCNC(N)=N)=O)N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)=O–Others–H2O–JNK—-MAPK/ERK Pathway–Peptides