Description

IMP-2373 is the activity-based probe (ABP). IMP-2373 is a covalent pan- deubiquitinase(DUB) ABP to monitor DUB activity in physiologically relevant live cells[1].–Applications–Formula-C21H20N4O2-Citation–References-[1]Daniel Conole, et al. Discovery of a Potent Deubiquitinase (DUB) Small-Molecule Activity-Based Probe Enables Broad Spectrum DUB Activity Profiling in Living Cells. Angew Chem Int Ed Engl. 2023, 62, 47.-CASNumber–MolecularWeight-360.41-Compound Purity–SMILES-C#CC1=CC=C(CNC(C2=CC(C(C3CN(C#N)CC3)=O)=CN2C)=O)C=C1-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-Deubiquitinase;Fluorescent Dye-Isoform–Pathway-Cell Cycle/DNA Damage;Others-MCE Product type-Dye Reagents