Description

:AbBy Fluor® 647;host:Rabbit;target_protein:IGF 2;modification:Unmodified;clonality:Polyclonal;isotype:IgG;concentration:1ug/ul;subcellular_locations:Secreted;source:KLH conjugated synthetic peptide derived from human IGF II;gene_id:3481;swiss_prot:P01344;applications_with_dilutions:WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200);cross_reactive_species:Human, Rat;predicted_cross_reactive_species:Mouse, Dog, Cow, Sheep, Pig, Rabbit;background:The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.;purification:Purified by Protein A.;storage_buffer:Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.;storage_condition:Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.;:650nm/665nm;synonyms:IGF-II; PP9974; C11orf43; Insulin-like growth factor II; Somatomedin-A; IGF2; PP1446