Description

:Unconjugated;host:Rabbit;target_protein:IDE;modification:Unmodified;clonality:Polyclonal;isotype:IgG;concentration:1ug/ul;subcellular_locations:Cytoplasm, Secreted, Cell membrane;source:KLH conjugated synthetic peptide derived from human IDE;gene_id:3416;swiss_prot:P14735;applications_with_dilutions:WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200);cross_reactive_species:Human, Mouse, Rat;predicted_cross_reactive_species:Cow, Pig, Chicken;background:Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.;purification:Purified by Protein A.;storage_buffer:0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.;storage_condition:Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.;:;synonyms:INSULYSIN; Insulin-degrading enzyme; Abeta-degrading protease; Insulin protease; Insulinase; IDE