Description

H3K27(Me2) (15-34), a histone peptide, is a repressive chromatin mark derived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27(Me)[1][2].—Cancer-programmed cell death–C86H154N30O25—-[1]Elizabeth T Wiles, et al. H3K27 Methylation: A Promiscuous Repressive Chromatin Mark. Curr Opin Genet Dev. 2017 Apr;43:31-37.|[2]Brian P Chadwick, et al. Multiple Spatially Distinct Types of Facultative Heterochromatin on the Human Inactive X Chromosome. Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17450-5.—-2008.36—-CN(CCCC[C@H](NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](C)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H]1N(C([C@H](C)N)=O)CCC1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CO)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(NCC(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)C–Cancer–10 mM in DMSO–Others—-Others–Peptides