H-Trp-Phe-OH-Get quote

Description

H-Trp-Phe-OH is a dipeptide consisting of tryptophan and phenylalanine (Trp-Phe). H-Trp-Phe-OH is also an antihypertensive peptide with inhibitory activity on angiotensin-converting enzyme (ACE), dose-dependently increases NO levels, and decreases endothelin-1 (ET-1) levels. H-Trp-Phe-OH (2 mg/kg; subcutaneous injection; 6 injections over 3 days) causes an increase in ovarian weight in female mice[1][2].—–C20H21N3O3—-[1]Zhao YQ, et al. Eight antihypertensive peptides from the protein hydrolysate of Antarctic krill (Euphausia superba): Isolation, identification, and activity evaluation on human umbilical vein endothelial cells (HUVECs). Food Res Int. 2019 Jul;121:197-204.|[2]Pitkow et al. Pharmacological effect of dipeptides on ovarian and uterine weights in immature mice. IRCS Medical Science: Library Compendium (1977), 5(8), 378.–6686-02-8–351.40—-OC([C@H](CC1=CC=CC=C1)NC([C@@H](N)CC2=CNC3=CC=CC=C23)=O)=O–Cardiovascular Disease–10 mM in DMSO–Angiotensin-converting Enzyme (ACE)—-Metabolic Enzyme/Protease–Peptides