Description

H-Ile-Pro-Pro-OH, a milk-derived peptide[1], inhibits angiotensin-converting enzyme (ACE)[1] with an IC50 of 5 μM[2]. Antihypertensive tripeptides[1].—Neuroscience-Neuromodulation–C16H27N3O4—-[1]Nonaka A, et al. The milk-derived peptides Val-Pro-Pro and Ile-Pro-Pro attenuate arterial dysfunction in L-NAME-treated rats. Hypertens Res. 2014 Aug;37(8):703-7.|[2]Nakamura Y, et al. Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk. J Dairy Sci. 1995 Apr;78(4):777-83.–26001-32-1–325.40—-O=C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(O)=O)=O)[C@H]([C@@H](C)CC)N–Cardiovascular Disease–10 mM in DMSO–Angiotensin-converting Enzyme (ACE)—-Metabolic Enzyme/Protease–Peptides