Guanosine triphosphate-15N5,d14 (dilithium)-Get quote
Description
Guanosine triphosphate-15N5,d14 (GTP-15N5,d14) dilithium is deuterium and 15N labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.–Applications-COVID-19-anti-virus-Formula-C10D14Li2 15N5O14P3-Citation–References-[1]Abdo A Elfiky, et al. Anti-HCV, nucleotide inhibitors, repurposing against COVID-19. Life Sci. 2020 May 1;248:117477.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.-CASNumber–MolecularWeight-554.10-Compound Purity–SMILES-O=P(O[2H])(O[Li])OP(OP(OC([2H])([2H])[C@@]1([2H])O[C@]([15N]2C([15N]=C([15N]([2H])[2H])[15N]([2H])C3=O)=C3[15N]=C2[2H])([2H])[C@](O[2H])([2H])[C@]1([2H])O[2H])(O[2H])=O)(O[Li])=O-Research_Area-Cancer; Infection-Solubility-10 mM in DMSO-Target-DNA/RNA Synthesis;Endogenous Metabolite;Isotope-Labeled Compounds;Nucleoside Antimetabolite/Analog;SARS-CoV-Isoform–Pathway-Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Others-MCE Product type-Isotope-Labeled Compounds