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GRP (porcine)

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Description

GRP (porcine) (Porcine gastrin-releasing peptide 27) is the putative mammalian analog of Bombesin (HY-P0195). GRP (porcine) activates the release of a number of gastroenteropancreatic (GEP) peptides into the peripheral circulation. GRP (porcine) stimulates gastrin release and exocrine pancreatic secretion. GRP (porcine) is a useful marker of neuroendocrine differentiation in many tumors[1][2].—–C126H198N38O31S2—-[1]Bostwick DG, Bensch KG. Gastrin releasing peptide in human neuroendocrine tumours. J Pathol. 1985 Dec;147(4):237-44.|[2]McDonald TJ, et al. The effect of gastrin-releasing peptide on the endocrine pancreas. Ann N Y Acad Sci. 1988;547:242-54.–74815-57-9–2805.29—-O=C([C@H]1N(CCC1)C([C@@H](NC([C@H](CCSC)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@@]([C@H](O)C)([H])NC(CNC(CNC(CNC([C@H](C(C)C)NC([C@H](CO)NC([C@H](C(C)C)NC([C@H]2N(CCC2)C([C@@H](N)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(O)C=C3)=O)N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CC4=CNC=N4)C(N[C@H](C(N[C@@H](C)C(N[C@@H](C(C)C)C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)CC5=CNC=N5)=O)=O)=O)=O)CC6=CNC7=C6C=CC=C7)=O)=O)=O)=O–Cancer–10 mM in DMSO–Others—-Others–Peptides

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MEDCHEM EXPRESS