Description

Globomycin is a lipopeptide antibiotic and a signal peptidase II (LspA) inhibitor. Globomycin inhibits processing of the prolipoprotein by binding irreversibly to the peptidase. Globomycin has toxic for the mollicute Spiroplasma melliferum with a MIC in the range 6.25-12.5 μM[1][2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)–COVID-19-immunoregulation–C32H57N5O9—-[1]Béven L, et al. Inhibition of spiralin processing by the lipopeptide antibiotic globomycin. Curr Microbiol. 1996 Nov;33(5):317-22.|[2]Parthasarathy S, et al. Organophosphate Hydrolase Is a Lipoprotein and Interacts with Pi-specific Transport System to Facilitate Growth of Brevundimonas diminuta Using OP Insecticide as Source of Phosphate. J Biol Chem. 2016 Apr 1;291(14):7774-85.–67076-74-8–655.82–99.0–CC(C)C[C@@](N(C([C@@H]([C@H](OC(CNC1=O)=O)CCCCCC)C)=O)C)([H])C(N[C@@](C(N[C@H](C(N[C@@]1([H])[C@@H](O)C)=O)CO)=O)([H])[C@H](C)CC)=O–Infection–10 mM in DMSO–Antibiotic;Bacterial–Lipopeptide–Anti-infection–Peptides