Description

GGGDTDTC-Mc-vc-PAB-MMAE is a Drug-Linker Conjugate for ADC, containing a tubulin inhibitor Monomethyl auristatin E (MMAE, HY-15162)[1].–Applications–Formula-C93H146N20O29S-Citation–References-[1]Zhao YJ, et al. Nanobody drug conjugate with high activity and application of GALA polypeptide in antibody drug conjugate. China, CN112807444 A. 2021-05-18. -CASNumber–MolecularWeight-2040.34-Compound Purity–SMILES-CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@@]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C3=CC=CC=C3)=O)([H])CCC2)=O)C)=O)=O)=O)C=C1)=O)=O)NC(CCCCCN4C(C(SC[C@@H](C(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(O)=O)NC(CNC(CNC(CN)=O)=O)=O)=O)=O)=O)=O)CC4=O)=O)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-Drug-Linker Conjugates for ADC;Microtubule/Tubulin-Isoform–Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton-MCE Product type-ADC Related