Description

GF109 is a potent parenteral inhibitor of angiotensin converting enzyme (ACE). GF109 has antihypertensive effects[1].—–C53H74N14O13—-[1]P Hatzinikolaou, et al. Comparative study of three parenteral inhibitors of the angiotensin converting enzyme. Biochem Pharmacol. 1981 Jul 1;30(13):1869-72.–79873-93-1–1115.24—-O=C(O)[C@H]1N(C([C@H]2N(C([C@H]([C@@H](C)CC)NC([C@H](CCC(N)=O)NC([C@H]3N(C([C@H](CCCNC(N)=N)NC([C@H]4N(C([C@H](CC5=CNC6=C5C=CC=C6)NC([C@H](CCC(O)=O)N)=O)=O)CC=C4)=O)=O)CCC3)=O)=O)=O)CCC2)=O)CC=C1–Cardiovascular Disease–10 mM in DMSO–Angiotensin-converting Enzyme (ACE)—-Metabolic Enzyme/Protease–Peptides