Description

Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG2-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].–20°C, 3 years; 4°C, 2 years (Powder)-Applications-Cancer-programmed cell death-Formula-C22H25NO6-Citation–References-[1]Fulcher JM, et al. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless “helping hand” solubilizing tag. Org Biomol Chem. 2019 Dec 28;17(48):10237-10244.-CASNumber-872679-70-4-MolecularWeight-399.44-Compound Purity-99.79-SMILES-O=C(O)CCOCCOCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O-Research_Area-Cancer-Solubility-DMSO : 125 mg/mL (ultrasonic)-Target-ADC Linker;PROTAC Linkers-Isoform-Cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related