Description

Fmoc-azetidine-3-carboxylic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.–20°C, 3 years; 4°C, 2 years (Powder)-Applications-Cancer-programmed cell death-Formula-C19H17NO4-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.-CASNumber-193693-64-0-MolecularWeight-323.35-Compound Purity-98.72-SMILES-C1=CC=CC2=C1C(C3=C2C=CC=C3)COC(=O)N4CC(C4)C(=O)O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related